I've just deployed full bundle instance of the 7.16.0.4461. There is no similar issue. The portal user profile page or organizational page and main page can be modified without any difficulties.
Try to perform these actions in the advanced settings that can help to resolve the issue:
1. Update database structure where needed
2. Generate the source code for all items
3.Compile all items
If there are still any difficulties, It is better to contact the support team via support@creatio.com to look into the issue in your particular environment.
There are no basic tools to set up a default startpage for particular roles, however, you can set up a startpage for a particular user separately. You can go to the System Users section, choose any user and indicate a Home page in the correspondent field - http://prntscr.com/log70b